GATE XL Biochemistry Syllabus
Complete section-wise syllabus for GATE XL Biochemistry section. This syllabus is prepared based on the latest official GATE notification and is regularly updated to reflect any changes announced by the exam authorities. Each section includes a detailed list of topics that candidates should study to prepare effectively for the exam.
6TopicsQ Section Code30 Marks
- Organization of life; Importance of water
- Structure and function of biomolecules: Amino acids, Carbohydrates, Lipids, Proteins and Nucleic acids
- Protein structure, folding/misfolding and function
- Myoglobin, Hemoglobin, Lysozyme, Ribonuclease A, Carboxypeptidase and Chymotrypsin
- Enzyme kinetics, regulation and inhibition; Vitamins and Coenzymes
- Bioenergetics and metabolism; Generation and utilization of ATP
- Metabolic pathways and their regulation: glycolysis, TCA cycle, pentose phosphate pathway, oxidative phosphorylation, gluconeogenesis, glycogen and fatty acid metabolism
- Metabolism of Nitrogen containing compounds: nitrogen fixation, amino acids and nucleotides
- Photosynthesis, Calvin cycle
- Biochemical separation techniques: Ion exchange, size exclusion and affinity chromatography, centrifugation
- Characterization of biomolecules by electrophoresis
- DNA-protein and protein-protein interactions
- UV-visible and fluorescence spectroscopy
- Mass spectrometry
- Cell structure and organelles; Biological membranes
- Action potential; Transport across membranes
- Membrane assembly and Protein targeting
- Signal transduction; Receptor-ligand interaction
- Hormones and neurotransmitters
- DNA replication, transcription and translation
- DNA damage and repair; Biochemical regulation of gene expression
- Recombinant DNA technology and applications: PCR, site directed mutagenesis, DNA-microarray
- Next generation sequencing
- Gene silencing and editing
- Immune System: Innate and adaptive; Cell of the immune system
- Active and passive immunity; Complement system
- Antibody structure, function and diversity; B cell and T Cell receptors; B cell and T cell activation
- Major histocompatibilty complex
- Immunological techniques: Immuno diffusion, immune-electrophoresis, RIA and ELISA, flow cytometry
- Monoclonal antibodies and their applications